Panton-Valentine leukocidin producing strains associated with serious community acquired S. aureus infection in Ireland
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چکیده
منابع مشابه
Panton-Valentine leukocidin in pediatric community-acquired Staphylococcus aureus infections.
PURPOSE Panton-Valentine Leukocidin (PVL) is an exotoxin produced by strains of Staphylococcus aureus (SA). Its importance as a virulence factor is controversial. We aim to further characterize the role of PVL in pediatric community-acquired SA infections. METHODS In a cohort study conducted from July to November 2006, we prospectively collected all strains of SA isolated at the Montreal Chil...
متن کاملPanton-Valentine Leukocidin–producing Staphylococcus aureus
To the Editor: Panton-Valentine leukocidin (PVL) is a cytotoxin produced by Staphylococcus aureus that causes leukocyte destruction and tissue necrosis (1). Although produced by <5% of S. aureus strains, the toxin is detected in large percentages of isolates that cause necrotic skin lesions and severe necrotizing pneumonia (2). Although commonly associated with community-acquired methicillin-re...
متن کاملPanton-Valentine leukocidin in community and hospital-acquired Staphylococcus aureus strains
Staphylococcus aureus causes serious hospital-acquired (HA) and community-acquired (CA) infections. Skin and soft-tissue infections especially are sometimes caused by strains harbouring Panton-Valentine leukocidin (PVL). PVL belongs to a family of bi-component leukocidal toxins produced by staphylococci. It is a pore-forming toxin encoded by lukF-PV and lukS-PV. A total of 70 S. aureus strains:...
متن کاملPediatric antibody response to community-acquired Staphylococcus aureus infection is directed to Panton-Valentine leukocidin.
We examined the antibody responses of pediatric patients infected with community-associated Staphylococcus aureus isolates. The data show that patients infected with Panton-Valentine leukocidin (PVL)-positive strains developed a dominant immunoglobulin G anti-PVL antibody response that correlates with markers of inflammation.
متن کاملEffect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin.
We examined the capacity of Staphylococcus aureus strains to release Panton-Valentine leukocidin (PVL) in the presence of antibiotics. No PVL was detected when S. aureus was incubated at inhibitory concentrations, while subinhibitory concentrations of oxacillin enhanced the PVL level; clindamycin, linezolid, and fusidic acid were inhibitory; and vancomycin had roughly no effect.
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ژورنال
عنوان ژورنال: Weekly releases (1997–2007)
سال: 2004
ISSN: 9999-1233
DOI: 10.2807/esw.08.44.02577-en